Limonin is a bitter component found in citrus fruits:<\/p>\n\n\n\n
1. Basic Information<\/p>\n\n\n\n
Name: Lemon Picricetin, English name Limonin, also known as Phellodendron Bark Lactone, Wuzhu Lactone.<\/p>\n\n\n\n
Molecular formula: C26H30O8<\/p>\n\n\n\n
Molecular weight: 470.53<\/p>\n\n\n\n
CAS Code: 1180-71-8<\/p>\n\n\n\n
Properties: Pure product is white crystalline, bitter taste. It also often exists in the form of yellowish brown or light yellow or white fine powder.<\/p>\n\n\n\n
Extract source: Mainly extracted from the seeds of citrus, grapefruit, lemon, orange, also exists in the peel but the content is less.<\/p>\n\n\n\n
2. Physical and Chemical Properties<\/p>\n\n\n\n
Solubility: citrinin is soluble in ester organic solvents, insoluble in water, but in methanol, ethanol solubility is greater.<\/p>\n\n\n\n
Melting point: 298\u00b0C.<\/p>\n\n\n\n
Stability: If used and stored in accordance with specifications, it will not decompose and has no known dangerous reactions, but oxides need to be avoided.<\/p>\n\n\n\n
3. Biological Activity and Efficacy<\/p>\n\n\n\n
Anti-cancer activity: Lemon Picricetin has been shown to be effective in inhibiting the growth of cancer cells, inhibiting the growth of a variety of cancer cell lines, including leukemia cells, cervical cancer cells, breast cancer cells, and hepatocellular carcinoma cells. Its anti-cancer mechanism may be related to the activation of glutathione transferase activity, the enzyme can inhibit the carcinogenic effect of chemical carcinogens.<\/p>\n\n\n\n
Analgesic and anti-inflammatory effects: experimental studies have shown that lemon bitterin has obvious analgesic and anti-inflammatory effects.<\/p>\n\n\n\n
Anxiolytic and sedative effects: lemon bitterin analogs can prolong the sleep time of mice induced by certain drugs, showing a certain anxiolytic and sedative effects.<\/p>\n\n\n\n
Insecticidal activity: Citraconidin analogs are active against insects and termites, and therefore have the potential to be developed into natural biological insecticides.<\/p>\n\n\n\n
Other effects: Citrulline also has antioxidant activity, antimicrobial properties, inhibition of HIV, lower cholesterol, obvious diuretic effect, improve cardiovascular circulation and improve sleep, regulation of cytochromes and other biological activities.<\/p>\n\n\n\n
In addition, there are studies showing that lemon bitter pigment has neuroprotective effect and anti-obesity effect.<\/p>\n\n\n\n
4. Application<\/p>\n\n\n\n
Functional food additives: lemon bitter pigment can be used as functional food additives, used in the production of anti-cancer food.<\/p>\n\n\n\n
Insecticide: Due to its insecticidal activity, lemon bitterin can be developed into a natural and non-toxic biopesticide.<\/p>\n\n\n\n
Feed additives: lemon bitterin can also be used as feed additives.<\/p>\n","protected":false},"excerpt":{"rendered":"
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